Oscar Isaac is facing annihilation…

The 37-year-old Guatemalan and Cuban American actor is in talks to reteam with Alex Garland, his director for the acclaimed sci-fi movie Ex Machina, for Annihilation, a post-apocalyptic horror adventure feature for Paramount Pictures.

Isaac, who was a standout as X-wing pilot Poe Dameron in the Star Wars: The Force Awakens, would star opposite Natalie Portman and Gina Rodriguez in the film, which is an adaptation of a book by Jeff VanderMeer.

The story follows a biologist, to be played by Portman, as she embarks on a four-person expedition into Area X, a territory cut off from civilization. While there, she must deal with a mysterious contamination, disappearing colleagues, a deadly animal and a being known as the Crawler, all while searching for clues regarding her husband’s disappearance.

Isaac will play Portman’s husband, who may not have disappeared after all.

Isaac starred with Alicia Vikander and Domhnall Gleeson in Ex Machina, in which he played the Steve Jobs-like owner of a search engine tech company creating artificial intelligence.

Star Wars: The Force Awakens, meanwhile, blasted box office records and currently has grossed over $933 million domestically, $2 billion worldwide