Edgar Ramirez’s gloves are on…

The Weinstein Company has released its latest trailer for Hands of Stone, the Roberto Duran boxing biopic starring the 39-year-old Venezuelan actor and Robert De Niro.

Duran became a hero in his native Panama as he rose through the ranks behind trainer Ray Arcel (De Niro), winning titles in four different weight classes. But it was his three epic bouts with Leonard that mattered most, the first when Duran beat Leonard to steal his welterweight belt in June 1980, and of course the second only five months later, when Duran famously told the referee “No mas” in the eighth round as Leonard was running circles around him. He also lost a close decision in a third fight in 1989. Duran certainly went on to redeem himself, though, and ended his career with 103 wins and securing his place on experts’ lists of the best fighters of all time.

Usher co-stars as Duran’s rival Sugar Ray Leonard, and Ellen Barkin, Ruben Blades and Ana de Armas co-star.

Hands of Stone debuts on August 26.