Lea Michele has a post-Glee layover…

The 28-year-old part-Spanish actress has been cast in in The Layover, the William H. Macy-directed road trip sex comedy written by David Hornsby and Lance Krall.

Michele and Kate Upton will portray a pair of lifelong best friends who decide to avoid their problems by taking a vacation only to find that their plane has been rerouted due to a hurricane warning. To make matters worse, the two friends find themselves battling for the same guy during an extended layover in St. Louis. Macy will play a role in the film as well.

“The minute I met Lea and Kate, the film began to focus for me,” said Macy, moonlighting from his series Shameless. “They are singular, ambitious funny women in full. This is going to be fun.”

Michele, who recently wrapped up the sixth and final season of Glee, has reteamed with Ryan Murphy on Fox’s anthology series Scream Queens.

Upton co-starred with Cameron Diaz and Leslie Mann in Fox’s The Other Woman.

Production on The Layover is imminent.