Selena Gomez has set her sights on her next film role…

The 22-year-old half-Mexican American actress and singer has landed the female lead opposite Paul Rudd in The Revised Fundamentals of Caregiving, directed by Emmy winner Rob Burnett.

Rudd will star in the indie drama as Ben, a caregiver looking after a frustrated teenager named Trevor who is in the advanced stages of Duchenne muscular dystrophy.

Gomez will portray Dot, a sassy young woman who hitches a ride with the pair during a road trip, and whose forwardness and lack of embarrassment about Trevor’s condition causes him to develop a crush on her.

Burnett, the veteran exec producer of The Late Show with David Letterman, adapted the script from Jonathan Evison’s 2013 novel of the same name.

Soon-to-be co-stars Gomez and Rudd were snapped Sunday night after the Golden Globes with writer/actor Justin Theroux, when a photo of the trio posted to Gomez’s Instagram garnered 1.1 million likes.

Filming on The Revised Fundamentals Of Caregiving begins January 22 in Atlanta.

It’s the latest indie film for Gomez, whose big screen credits include Sony’s 2012 animation hit Hotel Transylvania. A role in Harmony Korine’s racy Spring Breakers added street cred to her resume, and she was most recently seen in William H. Macy’s directorial debut Rudderless, which premiered last year at the Sundance Film Festival.

Gomez next reprises her voice role in Sony’s animated sequel Hotel Transylvania 2 opposite Adam Sandler and Andy Samberg. Offscreen, the global star who has over 107 million social media followers recently signed with Interscope Records after a long run with Disney’s Hollywood Records.