Alejandro Amenabar latest project will have its world premiere at one of the most important cinema festivals in the world.

The 43-year-old Spanish-Chilean director’s Regression will open the 63rd annual San Sebastian Film Festival as part of its world premiere.

“The world premiere of the film, presented in the Official Selection out of competition, will take place on September 18 in the Kursaal Auditorium,” the festival’s official website announced on Friday.

Ethan Hawke, Emma Watson, David Thewlis and David Dencik star in the psychological thriller, following in the path he forged with favorites like The Others and Open Your Eyes.

The story focuses on a detective, played by Hawke, who is investigating the claims of a young woman, Watson, who has accused her father, played by Dencik, of a crime that he has no recollection of committing.

When the father unexpectedly admits his guilt, a renowned psychologist, David Thewlis, is brought in to help the father rediscover his apparently repressed memories.

Regression is an English-language film shot in Canada, and will hit select cinemas just a few weeks after its screening in San Sebastian.

“Regression will open in Spain on October 2 followed by key territories, including Germany, the UK, France, Italy, China and Korea later this fall. The remaining worldwide releases will take place in the months to follow,” the announcement added.