Penelope Cruz has to Orient herself with a new project…

The 42-year-old Spanish actress is set to star in the Murder on the Orient Express remake.

Cruz joins a powerful ensemble cast that includes Johnny Depp, Michelle Pfeiffer, Daisy Ridley, Michael Pena, Judi Dench and Josh Gad along with Kenneth Branagh, who is starring as detective Hercule Poirot and also directing the film.

Based on the beloved 1934 Agatha Christie novel, the mystery begins after an American businessman is murdered aboard the train and the investigator tries to solve the murder, finding out eventually that 13 people all had something to do with the murder victim.

Cruz is currently shooting Escobar with husband Javier Bardem in the movie that examines the love affair between the drug lord Pablo Escobar and Colombian journalist Virginia Vallejo.